It is used in GTR and GBR procedures, socket and ridge preservation, ridge augmentation, Schneiderian membrane perforations, and peri-implant infections.
Biotivity™ A/C Plus Membrane
Growth-factor charged barrier

Biotivity A/C Plus Membrane: Powering Healing, Protecting Results.
Biotivity A/C Plus Membrane is a growth-factor rich bioactive barrier derived from human placental tissue. Consisting of the amnion, intermediate, and chorion layers, Biotivity A/C Plus is minimally manipulated using proprietary processing that preserves natural mechanical properties, elasticity, growth factors, and cytokines.1,2
Being a selective barrier, Biotivity A/C Plus Membrane provides a growth factor-enriched matrix that serves for the exchange of nutrients.
Biotivity A/C Plus Membrane Benefits
Enhancing regeneration, naturally.
Growth-factor charged performance
- Contains growth factors and cytokines which may contribute to healing1-3
- Acts as a scaffold for the migration and adhesion of cells4
- Shown to be antibacterial and non-immunologic5-7
Best-in-class processing
- Sterile product never delaminated and minimally manipulated to retain the natural tissue architecture and layers2
- No antibiotics utilized during processing2
- Terminally sterilized, SAL 10-6 8
The PLUS of the intermediate layer
- Natural triple-layer structure contributes to thickness and conformability9-11
- Enhances handling and stretchability11
- Provides additional collagen and biological enhancers like hyaluronic acid, shown to facilitate wound healing10-12
Biotivity A/C Plus Membrane Features
Osteoinductive Convenience and Choice
The membrane conforms nicely for site coverage or protection from the oral environment and may be suitable in a variety of regenerative procedures:
- GTR and GBR procedures13-16
- Socket and ridge preservation17,18
- Perforations of the Schneiderian membrane19,20
- Ridge augmentation15,21,22
- Peri-implant infections23,24
Trusted by Clinicians for Superior Handling & Healing
Join over 850 satisfied customers who have chosen Biotivity™ A/C Plus Membrane for predictable, high-quality healing in guided bone regeneration.
250+ Growth Factors for Enhanced Wound Healing
Minimal processed barrier, No Antibiotics
20,000+ Membranes Placed in North America
Proven performance in real-world clinical applications.
ZimVie is #2 in the Global Biomaterials Market
Trusted for its advanced biomaterials portfolio.
Frequently Asked Questions
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